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Kenneth O. Simbiri, MS, MRIPH, PhD.
President and CEO Trans-Africa Medical and Dental Consulting

Vision: Transformation of current strategies applied in prevention and intervention of communicable diseases (CD) and non- communicable diseases (NCD) in developing countries through early diagnosis and treatment by offering universal access to high quality health care. Striving for a world where most people have the best possible opportunity for health and well being, through work driven by integrity, diversity, team work, partnership, customer and results focus.

Mission: Transform the diagnosis, treatment, and prevention of CD and NCD(cancers, heart disease, obesity, and diabetes) in developing countries.Work on public health issues that impact developing nations and emerging markets. Strive to improve the efficacy and impact of new and existing health and development initiatives by bringing cutting-edge and innovative solutions to challenging global health problems. Offer high quality consultancy services focusing on fight against CD and NCD through innovation, information technology, creativity and effective execution.

Capacity building: Through empowering health workers to better serve communities in need around the world by improving health workers performance, skills, competencies, strengthening health systems and leveraging partnerships to overcome the causes of their exclusion and suffering.

Policy: Work with the governments and medical institutions on strategic health plans and goals that are sustainable especially for CD and NCD.

Services: Overview, strategy, implementation, research, clinical trials, evaluation, organizational change, coalition building.

Strategy: Help clients individually and collectively device clear goals and implement effective strategies applying resources to maximize outcome.

Implementation: Develop action plan meshing strategy with organizational realities supporting clients through broad societal participation and utilizing measurable impact by engaging all stakeholders (donors, consumers, and local experts).

Research: Research, publication(report findings), conferences.

Evaluation: Evaluation used to facilitate organization, community learning, make strategic decisions and informed decisions.

Organizational Change: Alignment of organizations and operations in support of strategies to ensure delivery of meaningful social impact.

Coalition Building: Build cross-sector collaborations of stakeholders uniting funders, nonprofits, governments, and corporations to achieve large-scale impact to solve health and social problems.

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About Us


Kenneth Simbiri, MS, MRIPH, PhD.

Viral Oncology, HIV/AIDS Consultant

Dr. Simbiri provides governments, academic institutions, Foundations, Non-Governmental Organizations, Pharmaceutical companies, and BIOTECH Start-ups coaching on setting up feasible studies/projects in Africa. Dr. Simbiri has a background in viral oncology (University of Pennsylvania) and HIV/AIDS research(New York University and Temple University) with wide experience of conducting studies in Africa. Dr. Simbiri has a wide network of African researchers in Cameron, Ethiopia, Kenya, Uganda, Tanzania, South Africa, Nigeria, Ghana, and Botswana.

With an extensive background in clinical, basic, and behavioral HIV work in the United States and Africa Dr. Simbiri is in a position to advise clients on how to set up and manage projects in Africa.

Why Our Program is Unique

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Protocol Design:

Knowledge Transfer:

New Studies:




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Representative Publications:

Amos Otedo, MB,Ch.B; M.Med.(Int.Med; Dip.Gastroenterology; Kenneth O. Simbiri, MS, PhD.; Vincent Were, PhD.; Omolo Ongati, BSc, Maths., MSc, Ph.D; Benson A Estambale, MB;Ch.B; MScDTM&H.Ph.D. Risk factors for liver Cancer in HIV endemic areas of Western Kenya.Infectious Agents and Cancer (2018) 13:41

Kenneth O. Simbiri. Reconsidering the diagnostic progression of Conjunctival cancers in Developing Countries. SciFed Journal of Ocular Biology. SF J Ocular Biology, 2018, 2:1

Cristiana Bellan, Polito Maria Sole, Barbarino Marcella, Polito Ennio, Kenneth O. Simbiri, Giacomina Massaro-Giordano, and Antonio Giordano. Bilateral lacrimal gland mantle cell lymphoma: case report and literature review. J Clin Exp Ophthalmol 2016, 7:6. DOI: 10.4172/2155-9570.1000615.

Simbiri KO, Williams CK, Macaluso M, Giordano A. Promoting Cancer Control in Africa With "Ubuntu": A Report of the African Organization For Research and Training in Africa (AORTIC) 10th Conference, 2015 in Marrakech, Morocco. J Cell Physiol. 2016 Nov 1.

Kenneth O. Simbiri, Ph.D, Hem C. Jha, Ph.D, Giacomina Massaro-Giordano, MD and Erle S. Robertson, Ph.D. Transformation of primary conjunctival cells transfected with papilloma and herpesvirus oncogenes. Cancer and Clinical Oncology, Vol. 5, No. 2, November 2016.

Rogena EA, Simbiri KO, De Falco G, Leoncini L, Ayers L, Nyagol J. A review of the pattern of AIDS defining, HIV associated neoplasms and premalignant lesions diagnosed from 2000-2011 at Kenyatta National Hospital, Kenya. Infect Agent Cancer. 2015 Aug 24;10:28. doi: 10.1186/s13027-015-0021-1. eCollection 2015.

Daud II, Coleman CB, Smith NA, Ogolla S, Simbiri K, Bukusi EA, Ng'ang'a ZW, Sumba PO, Vulule J, Ploutz-Snyder R, Dent AE, Rochford R. Breast Milk as a Potential Source of Epstein-Barr Virus Transmission Among Infants Living in a Malaria-Endemic Region of Kenya. J Infect Dis. 2015 May 17. pii: jiv290. [Epub ahead of print]

Kenneth O. Simbiri, Ph.D, Hem C. Jha, Ph.D, David H. Henry, MD, and Erle S. Robertson, Ph.D. Anal cancer Patients in a Metropolitan Hospital present infection with multiple oncogenic viruses. Cancer and Clinical Oncology, Vol. 4, No.2 2: 2015.

Kenneth O. Simbiri, Ph.D, Nicholas A. Smith¶, B.S, Richard Otieno¶, MSc., Eric E M. Wohlford, Ph.D, Ibrahim I. Daud, MSc., Sumba P. Odada, Ph.D, Frank Middleton, Ph.D, and Rosemary Rochford Ph.D. Epstein –Barr Virus Genetic Variation in Lymphoblastoid Cell Lines derived from Kenyan Pediatric Population. PLoS One. 2015 May 1;10(5):e0125420. doi: 10.1371/journal.pone.0125420. eCollection 2015.

Daud II1, Ogolla S, Amolo AS, Namuyenga E, Simbiri K, Bukusi EA, Ng'ang'a ZW, Ploutz-Snyder R, Sumba PO, Dent A, Rochford R. Plasmodium falciparum Infection is Associated with Epstein-Barr Virus Reactivation in Pregnant Women Living in Malaria Holoendemic Area of Western Kenya. Matern Child Health J. 2015 Mar;19(3):606-14. doi: 10.1007/s10995-014-1546-4.

Simbiri KO, Jha HC, Kayembe MK, Kovarik C, Robertson ES. Oncogenic viruses associated with vulva cancer in HIV-1 patients in Botswana. Infect Agent Cancer. 2014 Aug 24;9:28. doi: 10.1186/1750-9378-9-28. eCollection 2014.

Christopher KO Williams, D Cristina Stefan, Fiona Rawlinson, Kenneth Simbiri and Sam M Mbulaiteye. The African Organisation for Research and Training in Cancer and its conferences: a historical perspective and highlights of the Ninth International Conference, Durban, South Africa, 21–24 November 2013. ecancer 8 396 / DOI: 10.3332/ecancer.2014.396

Simbiri Kenneth O and Robertson Erle S. Conjunctival Carcinoma in: R. Yarchoan (ed.), Cancers in People with HIV and AIDS: Progress and Challenges, DOI 10.1007/978-1-4939-0859-2_25, © Springer Science+Business Media New York 2014

Martha Tesfalul, BA, Kenneth Simbiri PhD, Chikoti M. Wheat, BA, Didintle Motsepe, MMed, Hayley Goldbach, BS, Kathleen Armstrong, MD, Kathryn Hudson, MD, Mukendi K. Kayembe, MD, Erle Robertson, PhD, Carrie Kovarik, MD. Oncogenic Viral Prevalence in Invasive Vulvar Cancer Specimens from HIV Positive and Negative Women in Botswana. Int J of Gyn Cancers 2013.

Kenneth O. Simbiri & Erle S. Robertson. Characterization of the OSSN Microbiome in HIV-1 Infected Patients. Cancer and Clinical Oncology. 2012: 1(1):88-101.

Kenneth O. Simbiri, Hem C Jha, Richard D Dzeng, Giacomina Massaro-Giordano, Erle S Robertson. Cytokine and Chemokine Expression Profiles in HIV-1 Infected Patients with Ocular Surface Squamous Neoplasia from Botswana. Cancer and Clinical Oncology. 2012: 1 (2): 10-24.

Karolyn A. Wanat, Phillip D. Holler, Tzvete Dentchev, Kenneth Simbiri, Erle Robertson, John T. Seykora, & Misha Rosenbach. Viral-Associated Trichodysplasia: characterization of a novel polyoma virus infection with therapeutic insights. Arch Dermatol. 2012;148(2):219-223.

Kenneth O. Simbiri, Masanao Murakami, Michael Feldman., Andrew Steenhoff, Oathokwa Nkomazana, Gregory Bisson, & Erle S Robertson. Multiple oncogenic viruses identified in ocular surface squamous neoplasia in HIV-1 patients. Infectious Agents and Cancer 2010, 5:6 26 March 2010.

Kenneth Omollo A. Simbiri, Alice Hausman, Rose O. Wadenya and Jeffrey Lidicker. Access Impediments to Health Care and Social Services Between Anglophone and Francophone African Immigrants Living in Philadelphia with Respect to HIV/AIDS. Journal of Immigrant and Minority Health. J Immigrant Minority Health (2010) 12:569–579.

Mameli, G., Deshmane, S.L., Ghafouri, M., Cui, J., Simbiri, K., Khalili, K., Mukerjee, R., Dolei, A., Amini, S., & Sawaya, B.E. (2007). C/EBPbeta regulates human immunodeficiency virus 1 gene expression through its association with cdk9. J Gen Virol. 88 (pt2): 631-40.

Eldeen, MB., Deshmane, S.L., Simbiri, K, Khalili, K., Amini, S., & Sawaya, B.E. (2006).MH2 domain of Smad3 reduces HIV-1 Tat-induction of cytokine secretion. J.Neuroimmunol.176 (1-2):174-180.

Kim, J.J., Simbiri, K.A., Sin J., Dang, K., Oh, J., Dentchev, T., Lee, D., Nottingham, L.K., Chalian, A.A., McCallus, D., Ciccarelli, R., Agadjanyan, M.G., & Weiner, D.B. Cytokine molecular adjuvants modulate immune responses induced by DNA vaccine constructs for HIV-1 and SIV. Journal of Interferon and Cytokine Research 19(1): 77-84, 1999.

Bourinbaiar, A. & Ajuang-Simbiri, K. Simple procedure for estimating the efficiency of PCR.Molecular Biotechnology 6(1):87-89, 1996.

Pollack, H., Zhan, M.X., Moore, T., Simbiri, K.O., Krasinski, K., & Borkowsky, W. Ontogeny of anti-human immunodefficiency virus (HIV) antibody production in HIV-1 infected infants. Proceedings of the National Academy of Sciences of the United States of America. 90(6): 2340-2344, 1993.

Borkowsky, W., Moore, T., Krasinski, K., Simbiri, K.O., & Holtzman, R. Evolution of phenotypic memory T cells in HIV-1 infected infants and children. Clinical Immunology and Immunopathology 63(3): 280-284, 1992.

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